Projects
From molecular mechanisms using multi-omics to cardiometabolic and cognitive health across in vitro, animal and clinical studies - a path to precise nutrition
Past Projects
- Principal Investigator of the project entitled “Assessment of effects of lemon extract on diabetes, inflammation, gut microbiome and gut health in mice on western-type diet”, Ingredients by Nature
- Principal investigator of the project “Evaluation of sex dysmorphic neurocognitive protective properties and underlying multigenomic mechanism of action of epicatechin in diabetic mice”, Academic Federation Grant Proposal of University of California Davis
- Principal investigator of the project “Nutrigenomic modification by orange juice in normal-weight and obese male and female volunteers: integrated multigenomic study”, funded by Estado de São Paulo – FAPESP
- Investigator in the project “Women’s Cardiovascular and Brain Health”, funded by California cy pres Wyeth settlement award
- Investigator of the project “Orange juice, hesperidin and their role in vascular health benefits in humans”, funded by European Fruit Juice Association
- Principal investigator of the project “Investigation of cardiac protective effects of polyphenol-rich foods: pre-clinical and bioinformatic analysis of genomic data”, funded by French ministry of foreign affairs
- Principal investigator of the project “A systems biology approach to understand the health benefits of polyphenols”, France-UC-Davis collaborative project funded by France-Barkley Foundation
- Investigator in the project “Enhancing research and innovation capacity of Tubitak Food Institute on dietary polyphenols and bioavailability/bioefficacy”, funded by EU aiming to enhance networking activities between the research institutions of the Widening countries and internationally leading counterparts
- Principal investigator of the project “Impact of epicatechin metabolites on brain endothelial cell function and identification of mechanisms of action using integrated multi-omics approach”, industry-funded grant
- Investigator in the project “Cardiovascular, metabolic and sex effects on brain vascular and cognitive functions”, project funded by Treadwell Foundation
- Principal investigator of the project “Bioinformatic analyses of role of miRNAs in the prevention of endothelial dysfunction by dietary bioactives”, project funded by Region of Auvergne Rhône-Alpes, France
- Investigator in the project “Role of polyphenol-rich extracts from lemon and orange in prevention of cardiometabolic disorders and type 2 diabetes – impact on gut microbiome and circulating miRNA”, project funded by Brazilian Agency of Research, collaboration with the University of Sao Paolo, Brazil
- Principal investigator of the project “Integrated bioinformatic analysis of omics data from clinical and in vitro studies”, INRA (2015-2016)
- Co-Leader of working group 2 of the European COST Action POSITIVe (FA1403): “Interindividual variation in response to consumption of plant food bioactives regarding cardiometabolic diseases and determinants involved – search of target genes thought systematic bioinformatic analysis of published omics data from in-vitro, animal and human studies”, EU
- Principal investigator of the project “The impact of polyphenols on the expression of miRNAs and their target genes in endothelial cells”, Research Award given by the French Society of Nutrition
- Principal investigator of the project “Micronutrients and modulation of miRNA expression profile of endothelial microparticles in inflammatory stress”, INRA
- Co-PI of the research project “Effects of grapefruit juice consumption on vascular function and gene/miRNA expression – A human cross-over study”, Grant of Florida Department of Citrus, USA
- Principal investigator of the project “Determination of cellular and molecular mechanisms of orange juice polyphenols in human monocytes”, Grant of Florida Department of Citrus, Florida, USA
- Principal investigator of the project “Identification of cellular and molecular targets of plant bioactives on human blood cells”, Scientific project and exchanges of excellence with laboratory from the Institute for Medical Research, Belgrade, Serbia
- Task leader & Member of the Steering Committee of the European Project (FP7 – KBBE) FLAVIOLA “Targeted delivery of dietary flavanols for optimal human cell function: Effects on cardiovascular health”, EU
- Principal investigator of the project “Impact of polyphenols on disorders of cognition and mood in apoE-deficient mice: transcriptomic and behavioral studies”,
- Investigator of the project “Effect of the consumption of orange juice on vascular protection and immune function – A human study on the specific contribution of citrus flavanones”, Grant of Florida Department of Citrus, Florida, USA
- Principal investigator of the project “Polyphenols and expression of miRNAs”, INRA
- Task leader in the project “Role of anthocyanins in prevention of atherosclerosis development and endothelial cell dysfunction, and identification of underlying molecular mechanisms of action”, French Agency of Research
- Investigator of the project “Anti-atherogenic effect of blueberry extract rich in anthocyanins and identification of underlying mechanisms of action”, industry (Ferlux)-funded project
- Task leader of the European Project (FP6 – KBBE) FLAVO “Flavonoids in fruits and vegetables: their impact on food quality, nutrition and health”, EU